Pulmonary hemosiderosis in children with Down syndrome: a national experience.

ABSTRACT:

Background

Pulmonary hemosiderosis is a rare and complex disease in children. A previous study from the French RespiRare® network led to two important findings: 20% of the children presented with both pulmonary hemosiderosis and Down syndrome (DS), and at least one tested autoantibody was found positive in 50%. This study investigates the relationships between pulmonary hemosiderosis and DS.

Methods

Patients younger than 20 years old and followed for pulmonary hemosiderosis were retrieved from the RespiRare® database. Clinical, biological, functional, and radiological findings were collected, and DS and non-DS patients' data were compared.

Results

A total of 34 patients (22 girls and 12 boys) were included, among whom nine (26%) presented with DS. The mean age at diag

SUBMITTER: Alimi A 

PROVIDER: S-EPMC5910623 | biostudies-literature | 2018 Apr

REPOSITORIES: biostudies-literature