Maternal use of personal care products during pregnancy and risk of testicular germ cell tumors in sons.

ABSTRACT:

Background

The etiology of testicular germ cell tumors (TGCT) is poorly understood, however, exposure to endocrine disrupting chemicals (EDCs) may be related to increased risk. Personal care products, some of which contain EDCs, are widely used on a daily basis and are known to cross the placenta, be present in breastmilk, and are capable of inducing reproductive tract abnormalities. To determine the association between personal care product use during pregnancy and breastfeeding and TGCT risk, an analysis among mothers of TGCT cases and controls was conducted.

Methods

The US Servicemen's Testicular Tumor Environmental and Endocrine Determinants (STEED) study enrolled TGCT cases and controls and their mothers between 2002 and 2005. The current analysis examined personal care

SUBMITTER: Ghazarian AA 

PROVIDER: S-EPMC5911208 | biostudies-literature | 2018 Jul

REPOSITORIES: biostudies-literature