Dynamic fMRI networks predict success in a behavioral weight loss program among older adults.

ABSTRACT: More than one-third of adults in the United States are obese, with a higher prevalence among older adults. Obesity among older adults is a major cause of physical dysfunction, hypertension, diabetes, and coronary heart diseases. Many people who engage in lifestyle weight loss interventions fail to reach targeted goals for weight loss, and most will regain what was lost within 1-2 years following cessation of treatment. This variability in treatment efficacy suggests that there are important phenotypes predictive of success with intentional weight loss that could lead to tailored treatment regimen, an idea that is consistent with the concept of precision-based medicine. Although the identification of biochemical and metabolic phenotypes are one potential direction of research, neurobiologic

SUBMITTER: Mokhtari F 

PROVIDER: S-EPMC5911254 | biostudies-literature | 2018 Jun

REPOSITORIES: biostudies-literature