Epicardial Fat Thickness and Bone Mineral Content: The Healthy Twin Study in Korea.

ABSTRACT:

Background

The conventional concept of positive association between general obesity and bone health was challenged in recent studies reporting the different effects of specific fat deposition on bone health. In the present study, we investigated the association between epicardial fat and bone health.

Methods

We measured echocardiographic epicardial fat thickness (EFT) and bone mineral content (BMC) in a twin-family cohort of Koreans (n = 1,198; 525 men, 460 pre- and 213 post-menopausal women). A total 121 pairs of monozygotic twin (MZ) and 404 pairs of dizygotic twin and sibling pairs (DZ/Sib) were included.

Results

EFT was positively associated with BMC in total, as well as in three subgroups (β = 0.107, 0.076, and 0.058 for men, pre-, and post-menopausal women, resp

SUBMITTER: Lee DW 

PROVIDER: S-EPMC5911676 | biostudies-literature | 2018 May

REPOSITORIES: biostudies-literature