Effect of bacterial growth rate on bacteriophage population growth rate.

ABSTRACT: It is important to understand how physiological state of the host influence propagation of bacteriophages (phages), due to the potential higher phage production needs in the future. In our study, we tried to elucidate the effect of bacterial growth rate on adsorption constant (δ), latent period (L), burst size (b), and bacteriophage population growth rate (λ). As a model system, a well-studied phage T4 and Escherichia coli K-12 as a host was used. Bacteria were grown in a continuous culture operating at dilution rates in the range between 0.06 and 0.98 hr^-1 . It was found that the burst size increases linearly from 8 PFU·cell^-1 to 89 PFU·cell^-1 with increase in bacteria growth rate. On the other hand, adsorption constant and latent period were both decreasi

SUBMITTER: Nabergoj D 

PROVIDER: S-EPMC5911998 | biostudies-literature | 2018 Apr

REPOSITORIES: biostudies-literature