Ontology highlight
ABSTRACT:
SUBMITTER: Martinez-Guryn K
PROVIDER: S-EPMC5912695 | biostudies-literature | 2018 Apr
REPOSITORIES: biostudies-literature
Cell host & microbe 20180401 4
The gut microbiota play important roles in lipid metabolism and absorption. However, the contribution of the small bowel microbiota of mammals to these diet-microbe interactions remains unclear. We determine that germ-free (GF) mice are resistant to diet-induced obesity and malabsorb fat with specifically impaired lipid digestion and absorption within the small intestine. Small bowel microbes are essential for host adaptation to dietary lipid changes by regulating gut epithelial processes involv ...[more]