Accurate T₁ mapping of short T₂ tissues using a three-dimensional ultrashort echo time cones actual flip angle imaging-variable repetition time (3D UTE-Cones AFI-VTR) method.

ABSTRACT:

Purpose

To develop an accurate T₁ measurement method for short T₂ tissues using a combination of a 3-dimensional ultrashort echo time cones actual flip angle imaging technique and a variable repetition time technique (3D UTE-Cones AFI-VTR) on a clinical 3T scanner.

Methods

First, the longitudinal magnetization mapping function of the excitation pulse was obtained with the 3D UTE-Cones AFI method, which provided information about excitation efficiency and B₁ inhomogeneity. Then, the derived mapping function was substituted into the VTR fitting to generate accurate T₁ maps. Numerical simulation and phantom studies were carried out to compare the AFI-VTR method with a B₁ -uncorrected VTR method, a B₁ -uncorrected

SUBMITTER: Ma YJ 

PROVIDER: S-EPMC5912804 | biostudies-literature | 2018 Aug

REPOSITORIES: biostudies-literature