Toxicity implications for early life stage Japanese medaka (Oryzias latipes) exposed to oxyfluorfen.

ABSTRACT: We investigated the potential toxic effects of Oxyfluorfen (OXY), an herbicide used in agriculture, on the embryo-larval development of Japanese medaka fish (Oryzias latipes). Embryos (1-day postfertilization) and larvae (2-day posthatch) were exposed to OXY (0.5-8 mg/L) for 96 h and evaluated for mortality and hatching on embryos, and the mortality and growth on larvae during depuration. It was observed that the embryo-mortality was inconsistently altered by OXY; only the 2 mg/L group showed significant reduction on embryo survivability. However, larval-mortality was concentration-dependent and OXY exposure induced scoliosis-like phenotypic features in the surviving larvae; the calculated LC₅₀ was 5.238 mg/L. Our data further indicated that larval skeleton, both axial and appen

SUBMITTER: Powe DK 

PROVIDER: S-EPMC5912988 | biostudies-literature | 2018 May

REPOSITORIES: biostudies-literature