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Secondary Metabolites from the Endophytic Fungus Xylaria sp. hg1009.

ABSTRACT: A detailed chemical investigation of the secondary metabolites produced by the endophytic fungus Xylaria sp. isolated from the stems of Isodon sculponeatus afforded six new compounds, xylariahgins A-F (1-6), two new natural products (7 and 8), along with two known compounds (9 and 10) (Fig. 1). The structures of all compounds were unambiguously established by analyzing their spectroscopic data or referring to pertinent literature. Compounds 1-8 were tested for their cytotoxic activity against five human tumor cell lines.

SUBMITTER: Chen R 

PROVIDER: S-EPMC5913051 | biostudies-literature | 2018 Apr

REPOSITORIES: biostudies-literature

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Secondary Metabolites from the Endophytic Fungus Xylaria sp. hg1009.

Chen Rong R   Tang Jian-Wei JW   Li Xing-Ren XR   Liu Miao M   Ding Wen-Ping WP   Zhou Yuan-Fei YF   Wang Wei-Guang WG   Du Xue X   Sun Han-Dong HD   Puno Pema-Tenzin PT  

Natural products and bioprospecting 20180320 2

A detailed chemical investigation of the secondary metabolites produced by the endophytic fungus Xylaria sp. isolated from the stems of Isodon sculponeatus afforded six new compounds, xylariahgins A-F (1-6), two new natural products (7 and 8), along with two known compounds (9 and 10) (Fig. 1). The structures of all compounds were unambiguously established by analyzing their spectroscopic data or referring to pertinent literature. Compounds 1-8 were tested for their cytotoxic activity against fi  ...[more]

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