Aberrant salience network functional connectivity in auditory verbal hallucinations: a first episode psychosis sample.

ABSTRACT: Auditory verbal hallucinations (AVH) often lead to distress and functional disability, and are frequently associated with psychotic illness. Previously both state and trait magnetic resonance imaging (MRI) studies of AVH have identified activity in brain regions involving auditory processing, language, memory and areas of default mode network (DMN) and salience network (SN). Current evidence is clouded by research mainly in participants on long-term medication, with chronic illness and by choice of seed regions made 'a priori'. Thus, the aim of this study was to elucidate the intrinsic functional connectivity in patients presenting with first episode psychosis (FEP). Resting state functional MRI data were available from 18 FEP patients, 9 of whom also experienced AVH of sufficient duration

SUBMITTER: Mallikarjun PK 

PROVIDER: S-EPMC5913255 | biostudies-literature | 2018 Mar

REPOSITORIES: biostudies-literature