Ontology highlight
ABSTRACT:
SUBMITTER: Hoshina A
PROVIDER: S-EPMC5913312 | biostudies-literature | 2018 Apr
REPOSITORIES: biostudies-literature
Scientific reports 20180423 1
Cell therapy using renal progenitors differentiated from human embryonic stem cells (hESCs) or induced pluripotent stem cells (hiPSCs) has the potential to significantly reduce the number of patients receiving dialysis therapy. However, the differentiation cultures may contain undifferentiated or undesired cell types that cause unwanted side effects, such as neoplastic formation, when transplanted into a body. Moreover, the hESCs/iPSCs are often genetically modified in order to isolate the deriv ...[more]