How strong was the bottleneck associated to the peopling of the Americas? New insights from multilocus sequence data.

ABSTRACT: In spite of many genetic studies that contributed for a deep knowledge about the peopling of the Americas, no consensus has emerged about important parameters such as the effective size of the Native Americans founder population. Previous estimates based on genomic datasets may have been biased by the use of admixed individuals from Latino populations, while other recent studies using samples from Native American individuals relied on approximated analytical approaches. In this study we use resequencing data for nine independent regions in a set of Native American and Siberian individuals and a full-likelihood approach based on isolation-with-migration scenarios accounting for recent flow between Asian and Native American populations. Our results suggest that, in agreement with previous st

SUBMITTER: Fagundes NJR 

PROVIDER: S-EPMC5913727 | biostudies-literature | 2018

REPOSITORIES: biostudies-literature