Influence of Eimeria falciformis Infection on Gut Microbiota and Metabolic Pathways in Mice.

ABSTRACT: Coccidiosis, caused by different species of Eimeria parasites, is an economically important disease of poultry and livestock worldwide. Here we report previously unknown alterations in the gut microbes and metabolism of BALB/c mice infected with Eimeria falciformis Specifically, we observed a significant shift in the abundance of cecal bacteria and disrupted metabolism in parasitized animals. The relative abundances of Lachnospiraceae bacterium NK4A136, Ruminiclostridium, Alistipes, and Lactobacillus declined in response to E. falciformis infection, whereas Escherichia, Shigella, Helicobacter, Klebsiella, and Bacteroides were increased. Carbohydrate and amino acid metabolites in the serum samples of infecte

SUBMITTER: Huang G 

PROVIDER: S-EPMC5913850 | biostudies-literature | 2018 May

REPOSITORIES: biostudies-literature