Automated VMAT planning for postoperative adjuvant treatment of advanced gastric cancer.

ABSTRACT:

Background

Postoperative/adjuvant radiotherapy of advanced gastric cancer involves a large planning target volume (PTV) with multi-concave shapes which presents a challenge for volumetric modulated arc therapy (VMAT) planning. This study investigates the advantages of automated VMAT planning for this site compared to manual VMAT planning by expert planners.

Methods

For 20 gastric cancer patients in the postoperative/adjuvant setting, dual-arc VMAT plans were generated using fully automated multi-criterial treatment planning (autoVMAT), and compared to manually generated VMAT plans (manVMAT). Both automated and manual plans were created to deliver a median dose of 45 Gy to the PTV using identical planning and segmentation parameters. Plans were evaluated by two expert radiati

SUBMITTER: Sharfo AWM 

PROVIDER: S-EPMC5913894 | biostudies-literature | 2018 Apr

REPOSITORIES: biostudies-literature