Characterization, treatment and prognosis of retinoblastoma with central nervous system metastasis.

ABSTRACT:

Background

Retinoblastoma is the most common primary intraocular tumor and more and more attention has been paid to the developing countries. This study was aimed to evaluate the clinical features, treatment, and prognosis of retinoblastoma patients with central nervous system (CNS) metastasis in Beijing Tongren Hospital, one of the largest tertiary eye centers in China.

Methods

Clinical data of 31 consecutive retinoblastoma patients with CNS metastases, who were diagnosed at the Department of Pediatrics in Beijing Tongren Hospital between September 2005 and December 2015, were retrospective analyzed.

Results

The median age at presentation was 29 months (range from 5 to 108 months). Magnetic resonance imaging (MRI) results indicated that 16 patients (56.6%, 16/31) pre

SUBMITTER: Hu H 

PROVIDER: S-EPMC5914066 | biostudies-literature | 2018 Apr

REPOSITORIES: biostudies-literature