Can exercise delay transition to active therapy in men with low-grade prostate cancer? A multicentre randomised controlled trial.

ABSTRACT:

Introduction

Active surveillance is a strategy for managing low-risk, localised prostate cancer, where men are observed with serial prostate-specific antigen assessments to identify signs of disease progression. Currently, there are no strategies to support active surveillance compliance nor are there interventions that can prevent or slow disease progression, ultimately delaying transition to active treatment before it is clinically required. Recently, we proposed that exercise may have a therapeutic potential in delaying the need for active treatment in men on active surveillance.

Methods and analysis

A single-blinded, two arm, multicentre randomised controlled trial will be undertaken with 168 patients randomly allocated in a ratio of 1:1 to exercise or usual care. Exerci

SUBMITTER: Galvao DA 

PROVIDER: S-EPMC5914709 | biostudies-literature | 2018 Apr

REPOSITORIES: biostudies-literature