Heart rate phenotypes and clinical correlates in a large cohort of adults without sleep apnea.

ABSTRACT:

Background

Normal sleep is associated with typical physiological changes in both the central and autonomic nervous systems. In particular, nocturnal blood pressure dipping has emerged as a strong marker of normal sleep physiology, whereas the absence of dipping or reverse dipping has been associated with cardiovascular risk. However, nocturnal blood pressure is not measured commonly in clinical practice. Heart rate (HR) dipping in sleep may be a similar important marker and is measured routinely in at-home and in-laboratory sleep testing.

Methods

We performed a retrospective cross-sectional analysis of diagnostic polysomnography in a clinically heterogeneous cohort of n=1047 adults without sleep apnea.

Results

We found that almost half of the cohort showed an increase

SUBMITTER: Huang Z 

PROVIDER: S-EPMC5914741 | biostudies-literature | 2018

REPOSITORIES: biostudies-literature