Association of seasonal viral acute respiratory infection with pneumococcal disease: a systematic review of population-based studies.

ABSTRACT:

Objective

Animal and in vitro studies suggest that viral acute respiratory infection (VARI) can predispose to pneumococcal infection. These findings suggest that the prevention of VARI can yield additional benefits for the control of pneumococcal disease (PD). In population-based studies, however, the evidence is not in accordance, possibly due to a variety of methodological challenges and problems in these studies. We aimed to summarise and critically review the methods and results from these studies in order to inform future studies.

Methods

We conducted a systematic review of population-based studies that analysed the association between preceding seasonal VARI and subsequent PD. We searched MEDLINE, Embase and Global Health databases using tailored search strategies.

SUBMITTER: Li Y 

PROVIDER: S-EPMC5914779 | biostudies-literature | 2018 Apr

REPOSITORIES: biostudies-literature