Association between Exposure to <i>p,p</i>'-DDT and Its Metabolite <i>p,p</i>'-DDE with Obesity: Integrated Systematic Review and Meta-Analysis.

ABSTRACT:

Background

The prevalence of obesity is increasing in all countries, becoming a substantial public health concern worldwide. Increasing evidence has associated obesity with persistent pollutants such as the pesticide DDT and its metabolite p,p'-DDE.

Objectives

Our objective was to systematically review the literature on the association between exposure to the pesticide DDT and its metabolites and obesity to develop hazard identification conclusions.

Methods

We applied a systematic review-based strategy to identify and integrate evidence from epidemiological, in vivo, and in vitro studies. The evidence from prospective epidemiological studies was quantitatively synthesized by meta-analysis. We rated the body of evidence and integrated the streams o

SUBMITTER: Cano-Sancho G 

PROVIDER: S-EPMC5915185 | biostudies-literature | 2017 Sep

REPOSITORIES: biostudies-literature