Prenatal Fluoride Exposure and Cognitive Outcomes in Children at 4 and 6-12 Years of Age in Mexico.

ABSTRACT:

Background

Some evidence suggests that fluoride may be neurotoxic to children. Few of the epidemiologic studies have been longitudinal, had individual measures of fluoride exposure, addressed the impact of prenatal exposures or involved more than 100 participants.

Objective

Our aim was to estimate the association of prenatal exposure to fluoride with offspring neurocognitive development.

Methods

We studied participants from the Early Life Exposures in Mexico to Environmental Toxicants (ELEMENT) project. An ion-selective electrode technique was used to measure fluoride in archived urine samples taken from mothers during pregnancy and from their children when 6-12 y old, adjusted for urinary creatinine and specific gravity, respectively. Child intelligence was measured

SUBMITTER: Bashash M 

PROVIDER: S-EPMC5915186 | biostudies-literature | 2017 Sep

REPOSITORIES: biostudies-literature