Does colectomy predispose to small intestinal bacterial (SIBO) and fungal overgrowth (SIFO)?

ABSTRACT: OBJECTIVES:After subtotal colectomy, 40% of patients report chronic gastrointestinal symptoms and poor quality of life. Its etiology is unknown. We determined whether small intestinal bacterial overgrowth (SIBO) or small intestinal fungal overgrowth (SIFO) cause gastrointestinal symptoms after colectomy. METHODS:Consecutive patients with unexplained abdominal pain, gas, bloating and diarrhea (>1 year), and without colectomy (controls), and with colectomy were evaluated with symptom questionnaires, glucose breath test (GBT) and/or duodenal aspiration/culture. Baseline symptoms, prevalence of SIBO/SIFO, and response to treatment were compared between groups. RESULTS:Fifty patients with colectomy and 50 controls were evaluated. A significantly higher (p = 0.005) proportion of patients with co

SUBMITTER: Rao SSC 

PROVIDER: S-EPMC5915536 | biostudies-literature | 2018 Apr

REPOSITORIES: biostudies-literature