ROS scavenging Mn₃O₄ nanozymes for in vivo anti-inflammation.

ABSTRACT: Reactive oxygen species (ROS)-induced oxidative stress is linked to various diseases, including cardiovascular disease and cancer. Though highly efficient natural ROS scavenging enzymes have been evolved, they are sensitive to environmental conditions and hard to mass-produce. Therefore, enormous efforts have been devoted to developing artificial enzymes with ROS scavenging activities. Among them, ROS scavenging nanozymes have recently attracted great interest owing to their enhanced stability, multi-functionality, and tunable activity. It has been implicated that Mn-contained nanozymes would possess efficient ROS scavenging activities, however only a few such nanozymes have been reported. To fill this gap, herein we demonstrated that Mn₃O₄ nanoparticles (NPs) possess

SUBMITTER: Yao J 

PROVIDER: S-EPMC5915792 | biostudies-literature | 2018 Mar

REPOSITORIES: biostudies-literature