Progression of Primary Open-Angle Glaucoma in Diabetic and Nondiabetic Patients.

ABSTRACT:

Purpose

To compare the rates of visual field (VF) loss and retinal nerve fiber layer (RNFL) thinning in primary open-angle glaucoma (POAG) patients with or without type 2 diabetes mellitus (DM).

Design

Cohort study.

Methods

A total of 197 eyes (55 eyes of 32 POAG patients with DM in POAG/DM group and 142 eyes of 111 age-matched POAG patients without DM in POAG/DM- group) were included from the Diagnostic Innovations in Glaucoma Study (DIGS). Type 2 DM participants were defined by self-report of DM history and use of antidiabetic medication. The rates of VF loss and RNFL loss were compared in POAG eyes with and without DM using univariate and multivariable mixed-effects models.

Results

The median (interquartile range) follow-up was 5.7 years (4.0, 6.4). The mean

SUBMITTER: Hou H 

PROVIDER: S-EPMC5916320 | biostudies-literature | 2018 May

REPOSITORIES: biostudies-literature