Deletion at the 5'-end of Estonian ASFV strains associated with an attenuated phenotype.

ABSTRACT: African swine fever (ASF) was introduced into the Eastern European Union in 2014 and led to considerable mortality among wild boar. In contrast, unexpected high antibody prevalence was reported in hunted wild boar in north-eastern Estonia. One of the causative virus strains was recently characterized. While it still showed rather high virulence in the majority of experimentally infected animals, one animal survived and recovered completely. Here, we report on the follow-up characterization of the isolate obtained from the survivor in the acute phase of infection. As a first step, three in vivo experiments were performed with different types of pigs: twelve minipigs (trial A), five domestic pigs (trial B), and five wild boar (trial C) were inoculated. 75% of the minipigs and all domestic pi

SUBMITTER: Zani L 

PROVIDER: S-EPMC5916933 | biostudies-literature | 2018 Apr

REPOSITORIES: biostudies-literature