Identification of genomic regions and candidate genes for chicken meat ultimate pH by combined detection of selection signatures and QTL.

ABSTRACT: BACKGROUND:The understanding of the biological determinism of meat ultimate pH, which is strongly related to muscle glycogen content, is a key point for the control of muscle integrity and meat quality in poultry. In the present study, we took advantage of a unique model of two broiler lines divergently selected for the ultimate pH of the pectoralis major muscle (PM-pHu) in order to decipher the genetic control of this trait. Two complementary approaches were used: detection of selection signatures generated during the first five generations and genome-wide association study for PM-pHu and Sartorius muscle pHu (SART-pHu) at the sixth generation of selection. RESULTS:Sixty-three genomic regions showed significant signatures of positive selection. Out of the 10 most significant regions (dete

SUBMITTER: Bihan-Duval EL 

PROVIDER: S-EPMC5918591 | biostudies-literature | 2018 Apr

REPOSITORIES: biostudies-literature