Pulmonary arterial enlargement predicts long-term survival in COPD patients.

ABSTRACT:

Rationale

Pulmonary artery enlargement (PAE) is associated with exacerbations in Chronic Obstructive Pulmonary Disease (COPD) and with survival in moderate to severe patients. The potential role of PAE in survival prediction has not been compared with other clinical and physiological prognostic markers.

Methods

In 188 patients with COPD, PA diameter was measured on a chest CT and the following clinical and physiological parameters registered: age, gender, smoking status, pack-years history, dyspnea, lung function, exercise capacity, Body Mass Index, BODE index and history of exacerbations in year prior to enrolment. Proportional Cox regression analysis determined the best predictor of all cause survival.

Results

During 83 months (±42), 43 patients died. Age, pack-year

SUBMITTER: de-Torres JP 

PROVIDER: S-EPMC5918899 | biostudies-literature | 2018

REPOSITORIES: biostudies-literature