Response of Gut Microbiota to Metabolite Changes Induced by Endurance Exercise.

ABSTRACT: A few animal studies have shown that wheel running could reverse an unhealthy status by shifting the gut microbial composition, but no investigations have studied the effect of endurance running, such as marathon running, on human gut microbial communities. Since many findings have shown that marathon running immediately causes metabolic changes in blood, urine, muscles and lymph that potentially impact the gut microbiota (GM) within several hours. Here, we investigated whether the GM immediately responds to the enteric changes in amateur half-marathon runners. Alterations in the metabolic profile and microbiota were investigated in fecal samples based on an untargeted metabolomics methodology and 16S rDNA sequencing analysis. A total of 40 fecal metabolites were found significantly change

SUBMITTER: Zhao X 

PROVIDER: S-EPMC5920010 | biostudies-literature | 2018

REPOSITORIES: biostudies-literature