Complex regression Doppler optical coherence tomography.

ABSTRACT: We introduce a new method to measure Doppler shifts more accurately and extend the dynamic range of Doppler optical coherence tomography (OCT). The two-point estimate of the conventional Doppler method is replaced with a regression that is applied to high-density B-scans in polar coordinates. We built a high-speed OCT system using a 1.68-MHz Fourier domain mode locked laser to acquire high-density B-scans (16,000 A-lines) at high enough frame rates (∼100  fps) to accurately capture the dynamics of the beating embryonic heart. Flow phantom experiments confirm that the complex regression lowers the minimum detectable velocity from 12.25  mm  /  s to 374  μm  /  s, whereas the maximum velocity of 400  mm  /  s is measured without phase wrapping. Complex regression Doppler OCT also demonstrate

SUBMITTER: Elahi S 

PROVIDER: S-EPMC5920204 | biostudies-literature | 2018 Apr

REPOSITORIES: biostudies-literature