Effects of bacterial translocation on hemodynamic and coagulation parameters during living-donor liver transplant.

ABSTRACT:

Background

Bacterial translocation (BT) has been proposed as a trigger for stimulation of the immune system with consequent hemodynamic alteration in patients with liver cirrhosis. However, no information is available regarding its hemodynamic and coagulation consequences during liver transplantation.

Methods

We screened 30 consecutive adult patients undergoing living-donor liver transplant for the presence of BT. Bacterial DNA, Anti factor Xa (aFXa), thromboelastometry, tumor necrosis factor-α TNF-α, and interleukin-17 (IL-17) values were measured in sera before induction of anesthesia. Systemic hemodynamic data were recorded throughout the procedures.

Results

Bacterial DNA was detected in 10 patients (33%) (bactDNA(+)). Demographic, clinical, and hemodynamic data we

SUBMITTER: Moharem HA 

PROVIDER: S-EPMC5921288 | biostudies-literature | 2018 Apr

REPOSITORIES: biostudies-literature