Analysis of Theileria orientalis draft genome sequences reveals potential species-level divergence of the Ikeda, Chitose and Buffeli genotypes.

ABSTRACT:

Background

Theileria orientalis (Apicomplexa: Piroplasmida) has caused clinical disease in cattle of Eastern Asia for many years and its recent rapid spread throughout Australian and New Zealand herds has caused substantial economic losses to production through cattle deaths, late term abortion and morbidity. Disease outbreaks have been linked to the detection of a pathogenic genotype of T. orientalis, genotype Ikeda, which is also responsible for disease outbreaks in Asia. Here, we sequenced and compared the draft genomes of one pathogenic (Ikeda) and two apathogenic (Chitose, Buffeli) isolates of T. orientalis sourced from Australian herds.

Results

Using de novo assembled sequences and a single nucleotide variant (SNV) analysis pipeline, we found extensive genetic divergen

SUBMITTER: Bogema DR 

PROVIDER: S-EPMC5921998 | biostudies-literature | 2018 Apr

REPOSITORIES: biostudies-literature