Impact of white matter hyperintensities on the prognosis of cryptogenic stroke patients.

ABSTRACT:

Background

To our knowledge, little is known regarding whether white matter hyperintensities (WMH) affect the prognosis of cryptogenic stroke (CS) patients. Understanding this association may be helpful with expecting the prognosis of CS patients.

Methods

This retrospective observational study enrolled consecutive CS patients who underwent brain MRI and comprehensive cardiac evaluation. Severe WMH was defined as Fazekas' score ≥3. We defined poor functional outcome as modified Rankin Scale score ≥3 at 3 months. Long-term mortality and causes of death were identified using national death certificates and assessed by Kaplan-Meier method and regression analysis model.

Results

Among 2732 patients with first-ever ischemic stroke, 599 (21.9%) patients were classified as hav

SUBMITTER: Jeong SH 

PROVIDER: S-EPMC5922577 | biostudies-literature | 2018

REPOSITORIES: biostudies-literature