Characterization of recombination features and the genetic basis in multiple cattle breeds.

ABSTRACT:

Background

Crossover generated by meiotic recombination is a fundamental event that facilitates meiosis and sexual reproduction. Comparative studies have shown wide variation in recombination rate among species, but the characterization of recombination features between cattle breeds has not yet been performed. Cattle populations in North America count millions, and the dairy industry has genotyped millions of individuals with pedigree information that provide a unique opportunity to study breed-level variations in recombination.

Results

Based on large pedigrees of Jersey, Ayrshire and Brown Swiss cattle with genotype data, we identified over 3.4 million maternal and paternal crossover events from 161,309 three-generation families. We constructed six breed- and sex-specific

SUBMITTER: Shen B 

PROVIDER: S-EPMC5923192 | biostudies-literature | 2018 Apr

REPOSITORIES: biostudies-literature