Self-reported adherence and biomarker levels of CoQ10 and alpha-tocopherol.

ABSTRACT:

Purpose

Women with breast cancer were randomized to receive coenzyme Q10 (CoQ10) plus Vitamin E or placebo in a clinical trial. The objective of this evaluation is to examine the association between participant self-reported adherence to the study supplements and changes in plasma biomarker levels.

Patients and methods

Correlation coefficients quantified the association between changes in alpha-tocopherol and CoQ10 levels and the association between self-reported adherence and changes in biomarkers. Participants were categorized by self-reported adherence; Kruskal- Wallis tests compared changes in alpha-tocopherol and CoQ10 levels between self-reported adherence groups.

Results

Women (N=155) provided baseline and post-treatment biomarkers; 147 completed at least one d

SUBMITTER: Vitolins MZ 

PROVIDER: S-EPMC5923253 | biostudies-literature | 2018

REPOSITORIES: biostudies-literature