Relationships between digestive efficiency and metabolomic profiles of serum and intestinal contents in chickens.

ABSTRACT: The increasing cost of conventional feedstuffs has bolstered interest in genetic selection for digestive efficiency (DE), a component of feed efficiency, assessed by apparent metabolisable energy corrected to zero nitrogen retention (AMEn). However, its measurement is time-consuming and constraining, and its relationship with metabolic efficiency poorly understood. To simplify selection for this trait, we searched for indirect metabolic biomarkers through an analysis of the serum metabolome using nuclear magnetic resonance (¹H NMR). A partial least squares (PLS) model including six amino acids and two derivatives from butyrate predicted 59% of AMEn variability. Moreover, to increase our knowledge of the molecular mechanisms controlling DE, we investigated ¹H NMR metab

SUBMITTER: Beauclercq S 

PROVIDER: S-EPMC5923279 | biostudies-literature | 2018 Apr

REPOSITORIES: biostudies-literature