The Structure of the Lipid A from the Halophilic Bacterium Spiribacter salinus M19-40T.

ABSTRACT: The study of the adaptation mechanisms that allow microorganisms to live and proliferate in an extreme habitat is a growing research field. Directly exposed to the external environment, lipopolysaccharides (LPS) from Gram-negative bacteria are of great appeal as they can present particular structural features that may aid the understanding of the adaptation processes. Moreover, through being involved in modulating the mammalian immune system response in a structure-dependent fashion, the elucidation of the LPS structure can also be seen as a fundamental step from a biomedical point of view. In this paper, the lipid A structure of the LPS from Spiribacter salinus M19-40T, a halophilic gamma-proteobacteria, was characterized through chemical analyses and matrix-assisted laser desorption ioni

SUBMITTER: Barrau C 

PROVIDER: S-EPMC5923411 | biostudies-literature | 2018 Apr

REPOSITORIES: biostudies-literature