Genomic Characterization of Sixteen Yersinia enterocolitica-Infecting Podoviruses of Pig Origin.

ABSTRACT: Yersinia enterocolitica causes enteric infections in humans and animals. Human infections are often caused by contaminated pork meat. Y. enterocolitica colonizes pig tonsils and pigs secrete both the human pathogen and its specific bacteriophages into the stools. In this work, sixteen Y. enterocolitica-infecting lytic bacteriophages isolated from pig stools originating from several pig farms were characterized. All phages belong to the Podoviridae family and their genomes range between 38,391-40,451 bp in size. The overall genome organization of all the phages resembled that of T7-like phages, having 3-6 host RNA polymerase (RNAP)-specific promoters at the beginning of the genomes and 11-13 phage RNAP-specific promoters as well as 3-5 rho-independent terminators

SUBMITTER: Salem M 

PROVIDER: S-EPMC5923468 | biostudies-literature | 2018 Apr

REPOSITORIES: biostudies-literature