Time efficient whole-brain coverage with MR Fingerprinting using slice-interleaved echo-planar-imaging.

ABSTRACT: Magnetic resonance fingerprinting (MRF) is a promising method for fast simultaneous quantification of multiple tissue parameters. The objective of this study is to improve the coverage of MRF based on echo-planar imaging (MRF-EPI) by using a slice-interleaved acquisition scheme. For this, the MRF-EPI is modified to acquire several slices in a randomized interleaved manner, increasing the effective repetition time of the spoiled gradient echo readout acquisition in each slice. Per-slice matching of the signal-trace to a precomputed dictionary allows the generation of T₁ and T₂* maps with integrated B₁⁺ correction. Subsequent compensation for the coil sensitivity profile and normalization to the cerebrospinal fluid additionally allows for quantitat

SUBMITTER: Rieger B 

PROVIDER: S-EPMC5923901 | biostudies-literature | 2018 Apr

REPOSITORIES: biostudies-literature