Prenatal and early-life triclosan and paraben exposure and allergic outcomes.

ABSTRACT:

Background

In cross-sectional studies triclosan and parabens, ubiquitous ingredients in personal care and other products, are associated with allergic disease.

Objectives

We investigated the association between prenatal and early-life triclosan and paraben exposure and childhood allergic disease in a prospective longitudinal study.

Methods

Subjects were enrollees in the Vitamin D Antenatal Asthma Reduction Trial. Triclosan, methyl paraben, and propyl paraben concentrations were quantified in maternal plasma samples pooled from the first and third trimesters and urine samples from children at age 3 or 4 years. Outcomes were parental report of physician-diagnosed asthma or recurrent wheezing and allergic sensitization to food or environmental antigens based on serum spe

SUBMITTER: Lee-Sarwar K 

PROVIDER: S-EPMC5924494 | biostudies-literature | 2018 Jul

REPOSITORIES: biostudies-literature