The gene regulatory program of <i>Acrobeloides nanus</i> reveals conservation of phylum-specific expression.

ABSTRACT: The evolution of development has been studied through the lens of gene regulation by examining either closely related species or extremely distant animals of different phyla. In nematodes, detailed cell- and stage-specific expression analyses are focused on the model Caenorhabditis elegans, in part leading to the view that the developmental expression of gene cascades in this species is archetypic for the phylum. Here, we compared two species of an intermediate evolutionary distance: the nematodes C. elegans (clade V) and Acrobeloides nanus (clade IV). To examine A. nanus molecularly, we sequenced its genome and identified the expression profiles of all genes throughout embryogenesis. In comparison with C. elegans, A. nanus exhibits a much slower e

SUBMITTER: Schiffer PH 

PROVIDER: S-EPMC5924915 | biostudies-literature | 2018 Apr

REPOSITORIES: biostudies-literature