The Comorbidity Between Internet Gaming Disorder and Depression: Interrelationship and Neural Mechanisms.

ABSTRACT: Internet gaming disorder (IGD) is characterized by cognitive and emotional deficits. Previous studies have reported the co-occurrence of IGD and depression. However, extant brain imaging research has largely focused on cognitive deficits in IGD. Few studies have addressed the comorbidity between IGD and depression symptoms and underlying neural mechanisms. Here, we systematically investigated this issue by combining a longitudinal survey study, a cross-sectional resting-state functional connectivity (rsFC) study and an intervention study. Autoregressive cross-lagged modeling on a longitudinal dataset of college students showed that IGD severity and depression are reciprocally predictive. At the neural level, individuals with IGD exhibited enhanced rsFC between the left amygdala and right d

SUBMITTER: Liu L 

PROVIDER: S-EPMC5924965 | biostudies-literature | 2018

REPOSITORIES: biostudies-literature