Is Cancer Protective for Subsequent Alzheimer's Disease Risk? Evidence From the Utah Population Database.

ABSTRACT:

Objective

Several studies have suggested that cancer is associated with a reduced risk of the development of Alzheimer's disease (AD). This study seeks to improve our understanding of the association between cancer and the development of AD by showing how mortality selection alters this relationship.

Method

A retrospective cohort study was carried out examining 92,425 individuals (47,873 women and 44,552 men) from the Utah Population Database with and without a history of any primary cancer identified by the Utah Cancer Registry. All individuals were aged 65-79 years and free of dementia in 1992 and followed for upwards of 18 years (1992-2009) for AD ascertainment, which was identified using diagnostic information from Medicare claims data.

Results

We replicate previo

SUBMITTER: Hanson HA 

PROVIDER: S-EPMC5926998 | biostudies-literature | 2017 Oct

REPOSITORIES: biostudies-literature