Interleukins and their signaling pathways in the Reactome biological pathway database.

ABSTRACT: BACKGROUND:There is a wealth of biological pathway information available in the scientific literature, but it is spread across many thousands of publications. Alongside publications that contain definitive experimental discoveries are many others that have been dismissed as spurious, found to be irreproducible, or are contradicted by later results and consequently now considered controversial. Many descriptions and images of pathways are incomplete stylized representations that assume the reader is an expert and familiar with the established details of the process, which are consequently not fully explained. Pathway representations in publications frequently do not represent a complete, detailed, and unambiguous description of the molecules involved; their precise posttranslational state;

SUBMITTER: Jupe S 

PROVIDER: S-EPMC5927619 | biostudies-literature | 2018 Apr

REPOSITORIES: biostudies-literature