Automated vessel exclusion technique for quantitative assessment of hepatic iron overload by R2*-MRI.

ABSTRACT:

Background

Extraction of liver parenchyma is an important step in the evaluation of R2*-based hepatic iron content (HIC). Traditionally, this is performed by radiologists via whole-liver contouring and T2*-thresholding to exclude hepatic vessels. However, the vessel exclusion process is iterative, time-consuming, and susceptible to interreviewer variability.

Purpose

To implement and evaluate an automatic hepatic vessel exclusion and parenchyma extraction technique for accurate assessment of R2*-based HIC.

Study type

Retrospective analysis of clinical data.

Subjects

Data from 511 MRI exams performed on 257 patients were analyzed.

Field strength/sequence

All patients were scanned on a 1.5T scanner using a multiecho gradient echo sequence for clinical monit

SUBMITTER: Tipirneni-Sajja A 

PROVIDER: S-EPMC5927847 | biostudies-literature | 2018 Jun

REPOSITORIES: biostudies-literature