Predicted Bacterial Interactions Affect in Vivo Microbial Colonization Dynamics in Nematostella.

ABSTRACT: The maintenance and resilience of host-associated microbiota during development is a fundamental process influencing the fitness of many organisms. Several host properties were identified as influencing factors on bacterial colonization, including the innate immune system, mucus composition, and diet. In contrast, the importance of bacteria-bacteria interactions on host colonization is less understood. Here, we use bacterial abundance data of the marine model organism Nematostella vectensis to reconstruct potential bacteria-bacteria interactions through co-occurrence networks. The analysis indicates that bacteria-bacteria interactions are dynamic during host colonization and change according to the host's developmental stage. To assess the predictive power of inferred interactions,

SUBMITTER: Domin H 

PROVIDER: S-EPMC5928149 | biostudies-literature | 2018

REPOSITORIES: biostudies-literature