The use of del Nido cardioplegia in adult cardiac surgery: A prospective randomized trial.

ABSTRACT:

Objectives

The del Nido cardioplegia solution has been used extensively in congenital heart surgery for more than 20 years and more recently for adults. This randomized controlled trial examined whether expanding this technique to adult cardiac surgery confers benefits in surgical workflow and clinical outcome compared with blood-based cardioplegia.

Methods

Adult first-time coronary artery bypass grafting (CABG), valve, or CABG/valve surgery patients requiring cardiopulmonary bypass (CPB) were randomized to del Nido cardioplegia (n = 48) or whole blood cardioplegia (n = 41). Primary outcomes assessed myocardial preservation. Troponin I was measured at baseline, 2 hours after CPB termination, 12 and 24 hours after cardiovascular intensive care unit admission. Alpha was set at

SUBMITTER: Ad N 

PROVIDER: S-EPMC5929134 | biostudies-literature | 2018 Mar

REPOSITORIES: biostudies-literature