Enteropathogens and Gut Inflammation in Asymptomatic Infants and Children in Different Environments in Southern India.

ABSTRACT: Children in poor environmental conditions are exposed early and often to enteric pathogens, but within developing countries, heterogeneity in enteropathogen exposure in different settings and communities is rarely addressed. We tested fecal samples from healthy infants and children from two different environments in the same Indian town for gut enteropathogens and biomarkers of gut inflammation. A significantly higher proportion of infants and children from a poor semi-urban neighborhood (93%) had one or more enteropathogens than those from a medical college campus (71.7%). Infants and children from the poor neighborhood had an average of 3.3 (95% confidence interval [CI]: 2.9-3.7) enteropathogens compared with an average of 1.4 (95% CI: 1.0-1.7) enteropathogens in campus infants/children.

SUBMITTER: Praharaj I 

PROVIDER: S-EPMC5929183 | biostudies-literature | 2018 Feb

REPOSITORIES: biostudies-literature