Epidemiological, Serological, and Virological Features of Dengue in Nha Trang City, Vietnam.

ABSTRACT: Vietnam is endemic for dengue. We conducted a series of retrospective and prospective studies to characterize the epidemiology of dengue and population mobility patterns in Nha Trang city, Vietnam, with a view to rational design of trials of community-level interventions. A 10-year time series of dengue case notifications showed pronounced interannual variability, as well as spatial heterogeneity in ward-level dengue incidence (median annual coefficient of variation k = 0.47). Of 451 children aged 1-10 years enrolled in a cross-sectional serosurvey, almost one-third had evidence of a past dengue virus (DENV) infection, with older children more likely to have a multitypic response indicative of past exposure to ≥ 1 serotype. All four DENV serotypes were detected in hospitalized patie

SUBMITTER: Quyen DL 

PROVIDER: S-EPMC5929208 | biostudies-literature | 2018 Feb

REPOSITORIES: biostudies-literature