Selective recurrent laryngeal nerve stimulation using a penetrating electrode array in the feline model.

ABSTRACT:

Objectives/hypothesis

Laryngeal muscles (LMs) are controlled by the recurrent laryngeal nerve (RLN), injury of which can result in vocal fold (VF) paralysis (VFP). We aimed to introduce a bioelectric approach to selective stimulation of LMs and graded muscle contraction responses.

Study design

Acute experiments in cats.

Methods

The study included six anesthetized cats. In four cats, a multichannel penetrating microelectrode array (MEA) was placed into an uninjured RLN. For RLN injury experiments, one cat received a standardized hemostat-crush injury, and one cat received a transection-reapproximation injury 4 months prior to testing. In each experiment, three LMs (thyroarytenoid, posterior cricoarytenoid, and cricothyroid muscles) were monitored with an electromyograp

SUBMITTER: Haidar YM 

PROVIDER: S-EPMC5930155 | biostudies-literature | 2018 Jul

REPOSITORIES: biostudies-literature