Iron metabolism in critically ill patients developing anemia of inflammation: a case control study.

ABSTRACT:

Background

Anemia occurring as a result of inflammatory processes (anemia of inflammation, AI) has a high prevalence in critically ill patients. Knowledge on changes in iron metabolism during the course of AI is limited, hampering the development of strategies to counteract AI. This case control study aimed to investigate iron metabolism during the development of AI in critically ill patients.

Methods

Iron metabolism in 30 patients who developed AI during ICU stay was compared with 30 septic patients with a high Hb and 30 non-septic patients with a high Hb. Patients were matched on age and sex. Longitudinally collected plasma samples were analyzed for levels of parameters of iron metabolism. A linear mixed model was used to assess the predictive values of the parameters.

SUBMITTER: Boshuizen M 

PROVIDER: S-EPMC5930297 | biostudies-literature | 2018 May

REPOSITORIES: biostudies-literature