Economic analysis of oral dexamethasone for symptom relief of sore throat: the UK TOAST study.

ABSTRACT:

Objectives

To undertake an economic analysis assessing the cost-effectiveness of a single dose of oral dexamethasone compared with placebo for the relief of sore throat.

Design

A UK-based, multicentre, two arm, individually randomised, double blind trial.

Setting and population

Adults (≥18 years) with acute sore throat and painful swallowing judged to be infective in origin, recruited and randomised in primary care.

Intervention

a single dose of 10 mg oral dexamethasone compared with placebo given at primary care visit.

Main outcome

Incremental cost-effectiveness ratios (ICERs), cost per quality-adjusted symptom resolution using the EuroQol-five dimensions-five levels instrument, were estimated as part of a cost-utility analysis performed on an intention

SUBMITTER: Burns RM 

PROVIDER: S-EPMC5931286 | biostudies-literature | 2018 Apr

REPOSITORIES: biostudies-literature